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Results for "

human serum

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (1) Apical Sodium-Dependent Bile Acid Transporter (1) Bacterial (1) Beta-secretase (1) Biochemical Assay Reagents (3) CETP (1) Cholinesterase (ChE) (2) Cytochrome P450 (1) Dopamine Receptor (1) Endogenous Metabolite (6) Fluorescent Dye (2) GABA Receptor (1) Histamine Receptor (1) HIV (1) Interleukin Related (6) Liposome (1) NF-κB (1) NO Synthase (1) Phospholipase (2) Ser/Thr Protease (1) TNF Receptor (2) URAT1 (1) VD/VDR (2)
By Research Areas:	Cancer (4) Cardiovascular Disease (4) Endocrinology (1) Infection (2) Inflammation/Immunology (12) Metabolic Disease (6) Neurological Disease (3)

By Targets:

Antibiotic (1)

Apical Sodium-Dependent Bile Acid Transporter (1)

Bacterial (1)

Beta-secretase (1)

Biochemical Assay Reagents (3)

CETP (1)

Cholinesterase (ChE) (2)

Cytochrome P450 (1)

Dopamine Receptor (1)

Endogenous Metabolite (6)

Fluorescent Dye (2)

GABA Receptor (1)

Histamine Receptor (1)

HIV (1)

Interleukin Related (6)

Liposome (1)

NF-κB (1)

NO Synthase (1)

Phospholipase (2)

Ser/Thr Protease (1)

TNF Receptor (2)

URAT1 (1)

VD/VDR (2)

By Research Areas:

Cancer (4)

Cardiovascular Disease (4)

Endocrinology (1)

Infection (2)

Inflammation/Immunology (12)

Metabolic Disease (6)

Neurological Disease (3)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: SGK

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P1956

Human serum albumin 1 Publications Verification HSA	NF-κB NO Synthase	Cardiovascular Disease Inflammation/Immunology
Human serum albumin (HSA) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. Human serum albumin exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. Human serum albumin can block the inhibitory effect of GML on human T cells, providing protective function for T cells. Human serum albumin is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, NF-κB, and peroxynitrite (ONOO ⁻) in the vascular wall, contributing to the reduction of blood pressure .

HY-150097

*Recombinant Human* Serum Albumin(rHSA)**	Biochemical Assay Reagents	Others
Recombinant Human Serum Albumin (rHSA) is an active compound and possesses an identical conformation to plasma derived HSA. Recombinant Human Serum Albumin (rHSA) has no difference between rHSA and plasma derived HSA. Recombinant Human Serum Albumin (rHSA) has high efficacy of rHSA with little or no adverse reaction .

HY-P99397

Sonelokimab ALX 0761; M 1095	Interleukin Related	Inflammation/Immunology
Sonelokimab (ALX 0761; M 1095) is a trivalent nanobody comprised of monovalent camelid-derived nanobodies specific to human interleukin (IL)-17A, IL-17F, and human serum albumin VHHs. Sonelokimab has the potential for plaque-type psoriasis research .

HY-P99696

Lerodalcibep LIB003	Ser/Thr Protease	Cardiovascular Disease Metabolic Disease
Lerodalcibep (LIB003) is a recombinant fusion protein of a PCSK9-binding domain (adnectin) and human serum albumin. Lerodalcibep is a Lipid-lowering agent. Lerodalcibep can be used for the research of hypercholesterolemia and cardiovascular diseases .

HY-W011297

Methyl arachidonate Arachidonic acid methyl ester	Others	Metabolic Disease
Methyl arachidonate (Arachidonic acid methyl ester) is a fatty acid methyl ester resulting from the formal condensation of the carboxy group of arachidonic acid with methanol. Methyl arachidonate has activity of human blood serum metabolite .

HY-150978

DDAO-C6	Fluorescent Dye	Others
DDAO-C6 is a cridone ester derivative, highly specific fluorescence for detecting human serum albumin (HSA). DDAO-C6 acts as an enzymatic activatable near-infrared fluorescent probe in visually sensing endogenous lipase from gut microbes (Ex/Em=600/658 nm) .

HY-139248

Paclitaxel octadecanedioate	Others	Cancer
Paclitaxel octadecanedioate (compound PTX-FA18) is comprised of Paclitaxel (HY-B0015) conjugated to 1,18-octadecanedioic acid (HY-W005178). Paclitaxel octadecanedioate mixed with human serum albumin (HAS) is cytotoxic to HT-1080, PANC-1, HT-29 and Hela cells (IC₅₀s = 12, 2.48, 8.62, and 64.42 nM, respectively) .

HY-W007894

Dimethylmalonic acid	Endogenous Metabolite	Others
Dimethylmalonic acid is a short-chain dicarboxylic acid in human serum. Dimethylmalonic acid is also a volatile organic compound detected in alveolar breath .

HY-130434

12-SAHSA

Endogenous Metabolite Cancer

12-SAHSA is a fatty acid ester of hydroxy fatty acids (FAHFAs). 12-SAHSA decreases in the human serum of breast cancer .
HY-15331

VD3-d6

Vitamin D3-26,26,26,27,27,27-d₆
VD/VDR Metabolic Disease

VD3-d₆ is the deuterium labeled Vitamin D3; tools for determination of Vitamin D3 metabolites in human serum.

12-SAHSA	Endogenous Metabolite	Cancer
12-SAHSA is a fatty acid ester of hydroxy fatty acids (FAHFAs). 12-SAHSA decreases in the human serum of breast cancer .

VD3-d6 Vitamin D3-26,26,26,27,27,27-d₆	VD/VDR	Metabolic Disease
VD3-d₆ is the deuterium labeled Vitamin D3; tools for determination of Vitamin D3 metabolites in human serum.

HY-D0022

5-Aminofluorescein 5-AF	Fluorescent Dye	Others
5-Aminofluorescein (5-AF) is a fluorescence marker, covalently bound to human serum albumin. The excitation wavelength is 495 nm and the emission wavelength is 535 nm .

HY-108877

Cefepime hydrochloride BMY-28142 hydrochloride	Antibiotic Bacterial	Infection
Cefepime hydrochloride is a cephalosporin antibiotic agent. Cefepime hydrochloride has inhibitory activity against human serum paraoxonase-1 (hPON1) with an IC₅₀ value of 21.115 mM .

HY-130705A

Tachysterol 3

VD/VDR Endogenous Metabolite Metabolic Disease

Tachysterol 3 is a photoproduct of Previtamin D₃ (HY-130705) .

Tachysterol 3	VD/VDR Endogenous Metabolite	Metabolic Disease
Tachysterol 3 is a photoproduct of Previtamin D₃ (HY-130705) .

HY-116078

CKD-519	CETP	Cardiovascular Disease
CKD-519 is a selective and potent cholesteryl ester transfer protein (CETP) inhibitor, which inhibits CETP-mediated transfer of cholesteryl ester in human serum with an IC₅₀ of 2.3 nM .

HY-W011711

Benzarone Fragivix	URAT1	Metabolic Disease
Benzarone (Fragivix) is a potent human uric acid transporter 1 (hURAT1) inhibitor, with an IC₅₀ of 2.8 μM in oocyte. Benzarone could lower uric acid serum levels .

HY-N12329

Fumonisin B4

Others Others

Fumonisin B4 is a derivative of fumonisin. Fumonisin B4 has low albumin binding capacity .

Fumonisin B4	Others	Others
Fumonisin B4 is a derivative of fumonisin. Fumonisin B4 has low albumin binding capacity .

HY-P99796

Ozoralizumab ATN-103	TNF Receptor	Inflammation/Immunology
Ozoralizumab (ATN-103) is an anti-TNFα humanized antibody. Ozoralizumab is a humanized trivalent nanobody compound that consists of two anti-human TNFα nanobodies and an anti-human serum albumin (HSA) nanobody. Ozoralizumab can be used in research of arthritis .

HY-118870

γ-Globulins from human blood	Endogenous Metabolite	Inflammation/Immunology
γ-Globulins from human blood are a class of proteins in the blood. γ-Globulin is a protein fraction of blood serum containing many antibodies that protect against bacterial and viral infectious diseases. γ-Globulins from human blood is used for common variable immunodeficiency

HY-P99505

Ziltivekimab COR-001	Interleukin Related	Cardiovascular Disease Inflammation/Immunology
Ziltivekimab (COR-001) is a human anti-IL-6 monoclonal antibody that is effective in reducing serum CRP. Ziltivekimab has anti-inflammatory activity and may be used in studies of chronic systemic inflammation and cardiovascular disease associated with CKD .

HY-18780

RR6 2 Publications Verification	Others	Cancer
RR6 is a potent, selective, reversible, competitive and orally active vanin inhibitor with an IC₅₀ of 540 nM for recombinant vanin-1. RR6 also potently inhibits human, bovine and rat serum pantetheinase with IC₅₀ values of 40 nM, 41 nM and 87 nM, respectively .

HY-155305

BuChE-IN-9	Cholinesterase (ChE) Beta-secretase GABA Receptor	Neurological Disease
BuChE-IN-9 (compound 22a) is a potent *equine serum-derived BuChE (eqBuChE)* inhibitor with an IC₅₀ of 173 nM. BuChE-IN-9 also inhibits human BACE1, Aβ aggregation, mouse GABA transporter 1 (mGAT1) and mGAT4. BuChE-IN-9 has significant antiamnesic properties .

HY-145405

C12-200 5 Publications Verification	Liposome	Others
C12-200 is an ionizable cationic lipid and auxiliary lipid. C12-200 is commonly used for mRNA delivery. Administration of human erythropoietin (EPO) mRNA or factor VII siRNA increased and decreased serum factor VII levels, respectively, in LNPs mice containing C12-200 .

HY-P99385

Vobarilizumab ALX-0061	Interleukin Related	Inflammation/Immunology
Vobarilizumab (ALX-0061) is an anti-IL-6R monoclonal antibody (mAb) (K_d: 0.19 pM). Vobarilizumab consists of an anti-IL-6R domain and an anti-human serum albumin domain. Vobarilizumab can be used in the research of inflammatory autoimmune diseases, such as rheumatoid arthritis .

HY-13402

Varespladib 4 Publications Verification LY315920	Phospholipase	Inflammation/Immunology
Varespladib (LY315920) is a potent and selective group IIA, secretory phospholipase A₂ (sPLA₂) inhibitor with an IC₅₀ of 9 nM. Varespladib exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC₅₀s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively .

HY-112714

GSK3532795 BMS-955176	HIV	Infection
GSK3532795 (BMS-955176) is a potent, orally active, second-generation HIV-1 maturation inhibitor, with EC₅₀s of 1.9, 10.2, 2.7 and 13 nM for HIV-1 WT, HIV-1 WT(human serum), HIV-1 V370A, and HIV-1 ΔV370, respectively .

HY-13402A

Varespladib sodium 4 Publications Verification LY315920 sodium	Phospholipase	Inflammation/Immunology
Varespladib sodium (LY315920 sodium) is a potent and selective group IIA, secretory phospholipase A₂ (sPLA₂) inhibitor with an IC₅₀ of 9 nM. Varespladib sodium exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC₅₀s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively .

HY-N2252

Licarin A (+)-Licarin A
Licarin A ((+)-Licarin A), a neolignan, significantly and dose-dependently reduces TNF-α production (IC₅₀=12.6 μM) in dinitrophenyl-human serum albumin (DNP-HSA)-stimulated RBL-2H3 cells. Anti-allergic effects. Licarin A reduces TNF-α and PGD2 production, and COX-2 expression .

HY-146035

AChE-IN-14	Cholinesterase (ChE) Histamine Receptor	Neurological Disease
AChE-IN-14 (compound 5) is a potent cholinesterase inhibitor with IC₅₀s of 0.46 , 0.48, and 0.44 μM for electric eel acetylcholinesterase (eeAChE), human recombinant acetylcholinesterase (hAChE), and equine serum butyrylcholinesterase (eqBuChE), respectively. AChE-IN-14 exhibits high affinity toward human H₃ receptor (H₃R; K_i= 159.8 nM). AChE-IN-14 can be used for the research of Alzheimer’s disease .

HY-105184

YM511	Cytochrome P450	Endocrinology
YM511 is a highly specific non-steroidal aromatase inhibitor. YM511 inhibits aromatase activities in microsomes from rat ovary and human placenta competitively (IC50s of 0.4 and 0.12 nM, respectively). YM511 slightly inhibits production of other steroid hormones. YM511 has the potential for suppressing estrogen-dependent action research without affecting serum levels of other steroid hormones .

HY-15790

Elobixibat A 3309; AZD 7806	Apical Sodium-Dependent Bile Acid Transporter Interleukin Related TNF Receptor	Metabolic Disease Inflammation/Immunology
Elobixibat (A 3309; AZD 7806) is an orally effective Apical Sodium-Dependent Bile (IBAT) inhibitor, with an IC₅₀ value of 0.53 nM (human IBAT ), 0.13 nM (mouse IBAT), 5.8 nM (canine IBAT). Elobixibat lowers LDL cholesterol, increases serum GLP-1, promotes colon motility, and has the potential to treat metabolic syndrome. Elobixibat can be used to study constipation, dyslipidemia, non-alcoholic hepatitis, and liver tumors .

HY-113509

Lipoxin A4 1 Publications Verification LXA4	Interleukin Related Endogenous Metabolite	Inflammation/Immunology
Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties . Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes (NHEKs) associated with the ERK1/2 and NF-kB pathways . Lipoxin A4 inhibits serum amyloid A (SAA)-mediated IL-8 release with an IC₅₀ value of 25.74 nM .

HY-137307

Cholest-5-ene-3ß,22(S)-diol (22S)-Hydroxycholesterol	Others	Inflammation/Immunology
Cholest-5-ene-3ß,22(S)-diol ((22S)-Hydroxycholesterol) is an orally active oxysterol with no significant cytotoxic, oxidative, or inflammatory effects on human prokaryotic leukemia cells. Cholest-5-ene-3ß,22(S)-diol inhibits weight gain and increased serum triacylglycerol (TAG) levels in rat models .

HY-120987

Ethyl stearidonate	Biochemical Assay Reagents	Others
6,9,12,15-octadecatetraenoic acid (Glycerol α-monoelaidate) is a rare omega-3 series polyunsaturated fatty acid. In normal people, it accounts for less than 0.25% of serum phospholipid fatty acids. It is found in certain natural oils, such as echium and blackcurrant, and to the extent that these oils are incorporated into nutraceuticals, stearidonic acid can be an important polyunsaturated species in the human diet. Ethyl stearidonic acid, an ester of the free acid, is less water soluble but more suitable for formulating stearidonic acid-containing diets and dietary supplements.

HY-113509S

Lipoxin A4-d5 LXA4-d₅	Interleukin Related Endogenous Metabolite	Inflammation/Immunology
Lipoxin A4-d₅ is the deuterium labeled Lipoxin A4. Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties[1]. Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes (NHEKs) associated with the ERK1/2 and NF-kB pathways[2]. Lipoxin A4 inhibits serum amyloid A (SAA)-mediated IL-8 release with an IC50 value of 25.74 nM[3].

HY-N7864

all-cis-4,7,10,13,16-Docosapentaenoic acid all-cis-4,7,10,13,16-Docosapentaenoic acid; Osbond acid	Biochemical Assay Reagents	Others
Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.

HY-B1904A

Fluphenazine decanoate dihydrochloride	Dopamine Receptor	Neurological Disease
Fluphenazine decanoate dihydrochloride is a dopamine D₂ receptor inhibitor, is a long-acting phenothiazine neuroleptic. Fluphenazine can be used for schizophrenia research .

5-Aminofluorescein 5-AF	Fluorescent Dyes/Probes
5-Aminofluorescein (5-AF) is a fluorescence marker, covalently bound to human serum albumin. The excitation wavelength is 495 nm and the emission wavelength is 535 nm .

DDAO-C6	Fluorescent Dyes/Probes
DDAO-C6 is a cridone ester derivative, highly specific fluorescence for detecting human serum albumin (HSA). DDAO-C6 acts as an enzymatic activatable near-infrared fluorescent probe in visually sensing endogenous lipase from gut microbes (Ex/Em=600/658 nm) .

Cat. No.	Product Name	Type

HY-P1956

Human serum albumin 1 Publications Verification HSA	Native Proteins
Human serum albumin (HSA) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. Human serum albumin exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. Human serum albumin can block the inhibitory effect of GML on human T cells, providing protective function for T cells. Human serum albumin is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, NF-κB, and peroxynitrite (ONOO ⁻) in the vascular wall, contributing to the reduction of blood pressure .

Human serum albumin

1 Publications Verification

HSA

Native Proteins

Human serum albumin (HSA) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. Human serum albumin exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. Human serum albumin can block the inhibitory effect of GML on human T cells, providing protective function for T cells. Human serum albumin is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, NF-κB, and peroxynitrite (ONOO ⁻) in the vascular wall, contributing to the reduction of blood pressure .

HY-150097

*Recombinant Human* Serum Albumin(rHSA)**	Biochemical Assay Reagents
Recombinant Human Serum Albumin (rHSA) is an active compound and possesses an identical conformation to plasma derived HSA. Recombinant Human Serum Albumin (rHSA) has no difference between rHSA and plasma derived HSA. Recombinant Human Serum Albumin (rHSA) has high efficacy of rHSA with little or no adverse reaction .

HY-145405

C12-200 5 Publications Verification	Drug Delivery
C12-200 is an ionizable cationic lipid and auxiliary lipid. C12-200 is commonly used for mRNA delivery. Administration of human erythropoietin (EPO) mRNA or factor VII siRNA increased and decreased serum factor VII levels, respectively, in LNPs mice containing C12-200 .

HY-N7864

all-cis-4,7,10,13,16-Docosapentaenoic acid all-cis-4,7,10,13,16-Docosapentaenoic acid; Osbond acid	Biochemical Assay Reagents
Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.

all-cis-4,7,10,13,16-Docosapentaenoic acid

all-cis-4,7,10,13,16-Docosapentaenoic acid; Osbond acid

Biochemical Assay Reagents

Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.

HY-120987

Ethyl stearidonate	Biochemical Assay Reagents
6,9,12,15-octadecatetraenoic acid (Glycerol α-monoelaidate) is a rare omega-3 series polyunsaturated fatty acid. In normal people, it accounts for less than 0.25% of serum phospholipid fatty acids. It is found in certain natural oils, such as echium and blackcurrant, and to the extent that these oils are incorporated into nutraceuticals, stearidonic acid can be an important polyunsaturated species in the human diet. Ethyl stearidonic acid, an ester of the free acid, is less water soluble but more suitable for formulating stearidonic acid-containing diets and dietary supplements.

Ethyl stearidonate

Biochemical Assay Reagents

6,9,12,15-octadecatetraenoic acid (Glycerol α-monoelaidate) is a rare omega-3 series polyunsaturated fatty acid. In normal people, it accounts for less than 0.25% of serum phospholipid fatty acids. It is found in certain natural oils, such as echium and blackcurrant, and to the extent that these oils are incorporated into nutraceuticals, stearidonic acid can be an important polyunsaturated species in the human diet. Ethyl stearidonic acid, an ester of the free acid, is less water soluble but more suitable for formulating stearidonic acid-containing diets and dietary supplements.

Cat. No.	Product Name	Target	Research Area

HY-P99397

Sonelokimab ALX 0761; M 1095	Interleukin Related	Inflammation/Immunology
Sonelokimab (ALX 0761; M 1095) is a trivalent nanobody comprised of monovalent camelid-derived nanobodies specific to human interleukin (IL)-17A, IL-17F, and human serum albumin VHHs. Sonelokimab has the potential for plaque-type psoriasis research .

HY-P99796

Ozoralizumab ATN-103	TNF Receptor	Inflammation/Immunology
Ozoralizumab (ATN-103) is an anti-TNFα humanized antibody. Ozoralizumab is a humanized trivalent nanobody compound that consists of two anti-human TNFα nanobodies and an anti-human serum albumin (HSA) nanobody. Ozoralizumab can be used in research of arthritis .

HY-P99505

Ziltivekimab COR-001	Interleukin Related	Cardiovascular Disease Inflammation/Immunology
Ziltivekimab (COR-001) is a human anti-IL-6 monoclonal antibody that is effective in reducing serum CRP. Ziltivekimab has anti-inflammatory activity and may be used in studies of chronic systemic inflammation and cardiovascular disease associated with CKD .

HY-P99696

Lerodalcibep LIB003	Ser/Thr Protease	Cardiovascular Disease Metabolic Disease
Lerodalcibep (LIB003) is a recombinant fusion protein of a PCSK9-binding domain (adnectin) and human serum albumin. Lerodalcibep is a Lipid-lowering agent. Lerodalcibep can be used for the research of hypercholesterolemia and cardiovascular diseases .

HY-P99845

Dazodalibep

MEDI 4920; VIB 4920
Inhibitory Antibodies Others

Dazodalibep (MEDI 4920; VIB 4920) is a monoclonal antibody targeting CD40LG/TNFSF5 fused to human serum albumin ALB/HSA .

HY-P99458

Balugrastim CG 10639	Inhibitory Antibodies	Cancer
Balugrastim (CG 10639) is a novel long-acting recombinant granulocyte colony-stimulating factor (G-CSF) obtained by means of a genetic fusion between recombinant human serum albumin and granulocyte colony-stimulating factor. Balugrastim can be used for the research of breast cancer .

HY-P99385

Vobarilizumab ALX-0061	Interleukin Related	Inflammation/Immunology
Vobarilizumab (ALX-0061) is an anti-IL-6R monoclonal antibody (mAb) (K_d: 0.19 pM). Vobarilizumab consists of an anti-IL-6R domain and an anti-human serum albumin domain. Vobarilizumab can be used in the research of inflammatory autoimmune diseases, such as rheumatoid arthritis .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W007894

Dimethylmalonic acid	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Dimethylmalonic acid is a short-chain dicarboxylic acid in human serum. Dimethylmalonic acid is also a volatile organic compound detected in alveolar breath .

HY-130705A

Tachysterol 3	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	VD/VDR Endogenous Metabolite
Tachysterol 3 is a photoproduct of Previtamin D₃ (HY-130705) .

HY-118870

γ-Globulins from human blood	Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Inflammation/Immunology	Endogenous Metabolite
γ-Globulins from human blood are a class of proteins in the blood. γ-Globulin is a protein fraction of blood serum containing many antibodies that protect against bacterial and viral infectious diseases. γ-Globulins from human blood is used for common variable immunodeficiency

HY-113509

Lipoxin A4 1 Publications Verification LXA4	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Inflammation/Immunology	Interleukin Related Endogenous Metabolite
Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties . Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes (NHEKs) associated with the ERK1/2 and NF-kB pathways . Lipoxin A4 inhibits serum amyloid A (SAA)-mediated IL-8 release with an IC₅₀ value of 25.74 nM .

HY-N12329

Fumonisin B4	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Others
Fumonisin B4 is a derivative of fumonisin. Fumonisin B4 has low albumin binding capacity .

Species:	Human (21)
Tag:	His (16) SUMO (1) Tag Free (2) Avi (3) GST (3) Fc (2)
Source:	HEK293 (10) P. pastoris (2) Sf9 insect cells (5) E. coli (4)

Cat. No.	Compare	Product Name	Species	Source

HY-P7875

	Serum Albumin/ALB Protein, Human (P.pastoris) rHuserum Albumin; serum Albumin; HSA; ALB	Human	P. pastoris
	The serum albumin/ALB protein has multiple binding abilities and can bind water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin, and drugs. Its main effects include regulating blood colloid osmotic pressure to achieve homeostasis. Serum Albumin/ALB Protein, Human (P.pastoris) is the recombinant human-derived Serum Albumin/ALB protein, expressed by P. pastoris , with tag free. The total length of Serum Albumin/ALB Protein, Human (P.pastoris) is 585 a.a., with molecular weight of 55-80 kDa.

HY-P71277

	SAA4 Protein, Human (His) serum Amyloid A-4 Protein; Constitutively Expressed serum Amyloid A Protein; C-SAA; SAA4; CSAA	Human	E. coli
	SAA4 Protein, a notable acute phase reactant, plays a pivotal role in responding to physiological challenges. As a crucial apolipoprotein within the HDL complex, SAA4 regulates lipid metabolism and is integral to high-density lipoprotein dynamics. Elevated during acute phase responses, SAA4 underscores its significance in the adaptive mechanisms to diverse stressors. SAA4 Protein, Human (His) is the recombinant human-derived SAA4 protein, expressed by E. coli , with C-6*His labeled tag. The total length of SAA4 Protein, Human (His) is 112 a.a., with molecular weight of ~16 kDa.

HY-P78393

	Serum Albumin/ALB Protein, Human (HEK293, His-Avi) Albumin; ALB; serum albumin; ANALBA; FDAH; PRO0883; PRO0903; PRO1341	Human	HEK293
	Serum Albumin/ALB Protein has versatile binding capabilities, binding water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin, and drugs. Its primary role involves regulating blood colloidal osmotic pressure for homeostasis. ALB acts as a major transporter for zinc, binding 80% of plasma zinc, and 45% of circulating calcium and magnesium. It interacts with the bacterial siderophore enterobactin, inhibiting E. coli's iron uptake. ALB also engages with FCGRT, regulating homeostasis, and forms a covalently-linked complex with chromophore-bound alpha-1-microglobulin, highlighting diverse molecular interactions and maintaining functionality in fatty acid binding. Serum Albumin/ALB Protein, Human (HEK293, His-Avi) is the recombinant human-derived Serum Albumin/ALB protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of Serum Albumin/ALB Protein, Human (HEK293, His-Avi) is 585 a.a., with molecular weight of 69-70 kDa.

HY-P78077

	Serum Albumin/ALB Protein, Human (Biotinylated, HEK293, His-Avi) Albumin; ALB; serum albumin; ANALBA; FDAH; PRO0883; PRO0903; PRO1341	Human	HEK293
	Serum Albumin/ALB Protein has versatile binding capabilities, binding water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin, and drugs. Its primary role involves regulating blood colloidal osmotic pressure for homeostasis. ALB acts as a major transporter for zinc, binding 80% of plasma zinc, and 45% of circulating calcium and magnesium. It interacts with the bacterial siderophore enterobactin, inhibiting E. coli's iron uptake. ALB also engages with FCGRT, regulating homeostasis, and forms a covalently-linked complex with chromophore-bound alpha-1-microglobulin, highlighting diverse molecular interactions and maintaining functionality in fatty acid binding. Serum Albumin/ALB Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived Serum Albumin/ALB protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of Serum Albumin/ALB Protein, Human (Biotinylated, HEK293, His-Avi) is 585 a.a., with molecular weight of 69-70 kDa.

HY-P70985

SAA2 Protein, Human (His)

SAA; SAA2; serum Amyloid A2
Human E. coli

HY-P70510

	SAA1 Protein, Human (His) serum Amyloid A-1 Protein; SAA; SAA1	Human	E. coli
	SAA1 Protein, a major acute phase protein, forms a homohexamer comprising dimers of trimers. While the native form doesn't spontaneously form amyloid fibrils, partial proteolysis can induce amyloid fibril generation. SAA1 also serves as an apolipoprotein in the HDL complex and shows affinity for heparin. SAA1 Protein, Human (His) is the recombinant human-derived SAA1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of SAA1 Protein, Human (His) is 104 a.a., with molecular weight of ~14.0 kDa.

HY-P72024

	Growth Hormone R/GHR Protein, Human (HEK293, hFc) Somatotropin receptor serum-binding protein	Human	HEK293
	Growth Hormone R (GHR) is the receptor for pituitary growth hormone, crucial in postnatal body growth regulation. Binding to its ligand activates the JAK2/STAT5 pathway, facilitating intracellular signaling. The soluble form, GHBP (Growth Hormone Binding Protein), acts as a growth hormone reservoir in the bloodstream. GHBP may modulate or inhibit growth hormone signaling, contributing to intricate growth process regulation. Growth Hormone R/GHR Protein, Human (HEK293, hFc) is the recombinant human-derived Growth Hormone R/GHR protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Growth Hormone R/GHR Protein, Human (HEK293, hFc) is 238 a.a., with molecular weight of ~66 kDa.

HY-P70485

	Vitronectin Protein, Human (HEK293, His) 1 Publications Verification Vitronectin; VN; S-Protein; serum-Spreading Factor; V75; VTN	Human	HEK293
	Vitronectin is a multifunctional cell adhesion factor in serum and tissues that interacts with glycosaminoglycans and proteoglycans. It acts as an adhesion molecule between cells and the matrix, binding to specific integrins. Vitronectin Protein, Human (HEK293, His) is the recombinant human-derived Vitronectin protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Vitronectin Protein, Human (HEK293, His) is 459 a.a., with molecular weight of 60-80 kDa.

HY-P700413

	Growth Hormone R/GHR Protein, Human (Biotinylated, HEK293, mFc-Avi) Somatotropin receptor serum-binding protein	Human	HEK293
	Growth Hormone R (GHR) is the receptor for pituitary growth hormone, crucial in postnatal body growth regulation. Binding to its ligand activates the JAK2/STAT5 pathway, facilitating intracellular signaling. The soluble form, GHBP (Growth Hormone Binding Protein), acts as a growth hormone reservoir in the bloodstream. GHBP may modulate or inhibit growth hormone signaling, contributing to intricate growth process regulation. Growth Hormone R/GHR Protein, Human (Biotinylated, HEK293, mFc-Avi) is the recombinant human-derived Growth Hormone R/GHR protein, expressed by HEK293, with C-Avi, C-mFc labeled tag. The total length of Growth Hormone R/GHR Protein, Human (Biotinylated, HEK293, mFc-Avi) is 238 a.a., with molecular weight of 56.6 kDa.

HY-P70485G

	GMP Vitronectin Protein, Human (HEK293, His) Vitronectin; VN; S-Protein; serum-Spreading Factor; V75; VTN	Human	HEK293
	Vitronectin is a key cell adhesion factor in serum and tissues and plays a crucial role in cell interactions by binding to glycosaminoglycans and proteoglycans. It is recognized by specific integrins and serves as an important adhesion molecule, facilitating cell-matrix interactions. GMP Vitronectin Protein, Human (HEK293, His) is the recombinant human-derived Vitronectin protein, expressed by HEK293 , with C-6*His labeled tag. The total length of GMP Vitronectin Protein, Human (HEK293, His) is 459 a.a., with molecular weight of 60-80 kDa.

HY-P74623

	PON3 Protein, Human (S50N, sf9, His) serum paraoxonase/lactonase 3; PON3	Human	Sf9 insect cells
	PON3 is less active against organophosphates and aromatic carboxylic acid esters and is particularly capable of rapidly hydrolyzing lactones, including statin precursors such as lovastatin. It is capable of hydrolyzing aromatic lactones and specific 5- or 6-membered ring lactones, but is less efficient for simple or polar substituted lactones. PON3 Protein, Human (S50N, sf9, His) is the recombinant human-derived PON3 protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of PON3 Protein, Human (S50N, sf9, His) is 354 a.a., with molecular weight of ~45 kDa.

HY-P701783

	SGK Protein, Human (Sf9) SGK1; Serine/threonine-protein kinase Sgk1; serum/glucocorticoid-regulated kinase 1	Human	Sf9 insect cells
	SGK protein is a multifunctional serine/threonine protein kinase that complexly controls multiple cellular processes, including ion channel and transporter regulation, enzymatic activity, transcription factors, neuronal excitability, cell growth, proliferation, survival, and migration. and apoptosis. SGK Protein, Human (Sf9) is the recombinant human-derived SGK protein, expressed by Sf9 insect cells , with tag free. The total length of SGK Protein, Human (Sf9) is 371 a.a., .

HY-P77215

	SRFBP1 Protein, Human (sf9, His-GST) serum response factor-binding protein 1; p49/STRAP; SRFBP1	Human	Sf9 insect cells
	The SRFBP1 protein is a potential regulator of multiple cellular processes and is involved in aging-associated transcriptional activation of cardiac genes and the biosynthesis/processing of SLC2A4 in adipocytes. Its multifaceted effects extend into metabolic pathways, involving interactions with SRF and formation of complexes with SRF cofactors ARID2, MYOCD, and NKX2-5, highlighting its role in transcriptional regulation. SRFBP1 Protein, Human (sf9, His-GST) is the recombinant human-derived SRFBP1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of SRFBP1 Protein, Human (sf9, His-GST) is 429 a.a., with molecular weight of ~69 kDa.

HY-P701782

	SGK2 Protein, Human (Sf9, GST) SGK2; Serine/threonine-protein kinase Sgk2; serum/glucocorticoid-regulated kinase 2	Human	Sf9 insect cells
	The SGK2 protein is a serine/threonine protein kinase that complexly regulates multiple cellular processes, overseeing ion channels, membrane transporters, and critical aspects of cell growth, survival, and proliferation. Its effects include upregulation of key components such as Na(+) and K(+) channels, amino acid and glutamate transporters, receptors, Na(+)/H(+) exchangers, and Na(+)/K(+) ATPase. SGK2 Protein, Human (Sf9, GST) is the recombinant human-derived SGK2 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of SGK2 Protein, Human (Sf9, GST) is 426 a.a., .

HY-P701784

	SGK Protein, Human (Sf9, His, GST) SGK1; Serine/threonine-protein kinase Sgk1; serum/glucocorticoid-regulated kinase 1	Human	Sf9 insect cells
	SGK protein is a multifunctional serine/threonine protein kinase that complexly controls multiple cellular processes, including ion channel and transporter regulation, enzymatic activity, transcription factors, neuronal excitability, cell growth, proliferation, survival, and migration. and apoptosis. SGK Protein, Human (Sf9, His, GST) is the recombinant human-derived SGK protein, expressed by Sf9 insect cells , with N-8*His, N-GST labeled tag. The total length of SGK Protein, Human (Sf9, His, GST) is 371 a.a., .

HY-P71067

	Pentraxin 2/SAP Protein, Human (HEK293, His) serum Amyloid P-Component; SAP; 9.5S Alpha-1-Glycoprotein; APCS; PTX2	Human	HEK293
	Pentraxin 2/SAP protein, a member of the pentraxin family, promotes innate immunity by recognizing pathogens and promoting their clearance. This soluble pattern recognition receptor is involved in multiple inflammatory processes, including complement activation, opsonization, and immune response regulation. Pentraxin 2/SAP Protein, Human (HEK293, His) is the recombinant human-derived Pentraxin 2/SAP protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Pentraxin 2/SAP Protein, Human (HEK293, His) is 204 a.a., with molecular weight of ~30.0 kDa.

HY-P72204

	Growth Hormone R/GHR Protein, Human (His-SUMO) GH receptor; GH-binding protein; GHBP; GHBP, included; GHR; GHR_human; Growth hormone binding protein; Growth hormone receptor; Growth hormone receptor precursor; Growth hormone-binding protein; Growth hormone-binding protein, included; Increased responsiveness to growth hormone, included; serum binding protein; serum-binding protein; Somatotropin receptor	Human	E. coli
	Growth Hormone R (GHR) is the receptor for pituitary growth hormone, crucial in postnatal body growth regulation. Binding to its ligand activates the JAK2/STAT5 pathway, facilitating intracellular signaling. The soluble form, GHBP (Growth Hormone Binding Protein), acts as a growth hormone reservoir in the bloodstream. GHBP may modulate or inhibit growth hormone signaling, contributing to intricate growth process regulation. Growth Hormone R/GHR Protein, Human (His-SUMO) is the recombinant human-derived Growth Hormone R/GHR protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of Growth Hormone R/GHR Protein, Human (His-SUMO) is 246 a.a., with molecular weight of ~44.4 kDa.

HY-P75173

	GASP-1/WFIKKN2 Protein, Human (HEK293, His) Growth and differentiation factor-associated serum protein 1; GASP-1; WFIKKN2; WFIKKNRP	Human	HEK293
	GASP-1/WFIKKN2, a multifaceted protease inhibitor with distinct domains, potentially inhibits serine proteases and metalloproteases. Its intriguing role involves inhibiting mature myostatin activity, leaving activin unaffected. GASP-1/WFIKKN2's engagement with both mature and propeptide forms of myostatin/MSTN adds complexity to the regulatory landscape of protease activities in biological systems. GASP-1/WFIKKN2 Protein, Human (HEK293, His) is the recombinant human-derived GASP-1/WFIKKN2 protein, expressed by HEK293 , with C-His labeled tag. The total length of GASP-1/WFIKKN2 Protein, Human (HEK293, His) is 542 a.a., with molecular weight of ~70-75 kDa.

HY-P71821

	PTK7 Protein, Human (P.pastoris, His) CCK 4; CCK-4; Colon carcinoma kinase 4; Inactive tyrosine-protein kinase 7; serum response factor; Srf; Tyrosine-protein kinase-like 7	Human	P. pastoris
	The PTK7 protein is an inactive tyrosine kinase that plays a key role in both non-canonical and canonical Wnt signaling pathways. Effects include cell adhesion, migration, polarity, proliferation, actin cytoskeleton reorganization, and apoptosis. PTK7 Protein, Human (P.pastoris, His) is the recombinant human-derived PTK7 protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of PTK7 Protein, Human (P.pastoris, His) is 674 a.a., with molecular weight of ~76.6 kDa.

HY-P7740

	Carnosine Dipeptidase 1/CNDP1 Protein, Human (HEK293, His) rHuCarnosine Dipeptidase 1, His; Beta-Ala-His Dipeptidase; CNDP Dipeptidase 1; Carnosine Dipeptidase 1; Glutamate Carboxypeptidase-Like Protein 2; serum Carnosinase; CNDP1; CN1; CPGL2	Human	HEK293
	Carnosine Dipeptidase 1 Protein, Human (HEK293, His) is a human carnosine dipeptidase 1 protein with a his-flag, expressed in HEK293 cells. Carnosine Dipeptidase 1 is a member of the M20 metalloprotease family, encoded by the CNDP1 gene.

HY-P70407

	ITIH3 Protein, Human (HEK293, His) rHuInter-alpha-trypsin inhibitor heavy chain H3/ITIH3/, His; Inter-alpha-trypsin inhibitor heavy chain H3; ITI heavy chain H3; ITI-HC3; Inter-alpha-inhibitor heavy chain 3; serum-derived hyaluronan-associated protein; SHAP	Human	HEK293
	The ITIH3 protein has a dual role: as a carrier of hyaluronic acid in serum and as a binding protein that facilitates interactions with various matrix proteins. These interactions regulate the localization, synthesis, and degradation of hyaluronic acid, which is critical for multiple cellular activities. ITIH3 Protein, Human (HEK293, His) is the recombinant human-derived ITIH3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of ITIH3 Protein, Human (HEK293, His) is 617 a.a., with molecular weight of ~90.0 kDa.

Cat. No.	Product Name	Chemical Structure

HY-15331

VD3-d6

VD3-d₆ is the deuterium labeled Vitamin D3; tools for determination of Vitamin D3 metabolites in human serum.

HY-113509S

Lipoxin A4-d5

Lipoxin A4-d₅ is the deuterium labeled Lipoxin A4. Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties[1]. Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes (NHEKs) associated with the ERK1/2 and NF-kB pathways[2]. Lipoxin A4 inhibits serum amyloid A (SAA)-mediated IL-8 release with an IC50 value of 25.74 nM[3].

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